Course Catalog 2007-2008

MIT-4076 BIOSENSORS, 5 cr
Biosensors

Courses persons responsible
Jukka Lekkala

Lecturers
Jukka Lekkala

Implementations
  Period 1 Period 2 Period 3 Period 4 Period 5 Summer
Lecture - - 2 h/week 2 h/week - -
Exercise - - 1 h/week 2 h/week - -
Exam  
(Timetable for academic year 2007-2008)

Objectives
Introduces basic principles and techniques used in biosensors. Gives information on applications.

Content
Content Core content Complementary knowledge Specialist knowledge
1. History of biosensor development, applications and requirements of biosensors.   Definition of concentrations, sampling principles    
2. Principles of molecular recognition, structure of enzyme and antibody, immunosensors, modeling of reactions, immobilization techniques.  Immune response, bacteria and viruses, self-assembled membranes  Molecular modeling, Langmuir-Blodgett -thin film technology 
3. Detection methods, electrodes, ISFET, optical sensors, Surface Plasmon Resonance (SPR) sensor, piezoelectric resonators and thermal sensors.   Principles of electrochemistry, operation principles of optical fibre sensors, modeling of SPR sensor.     
4. Miniaturization, biocompatibility, microanalyzers and BioMEMS structures.   Biomaterials, Micro ElectroMechanical systems (MEMS)    
5. Examples of commercial biosensors.       

Requirements for completing the course
Passed exercises and examination.

Evaluation criteria for the course

  • Credit points earned from the examination and bonus from exercises specify the mark for the course.

  • Used assessment scale is numeric (1-5)

    • Study material
    Type Name Auhor ISBN URL Edition, availability... Exam material Language
    Book Biomolecular sensors Gizeli and Lowe 0-7484-0791-X     Yes  English 
    Book Engineering Biosensors - Kinetics and Design Applications Ajit Sadana 0-12-613763-3 www.academicpress.com   No  English 
    Lecture slides Biosensors Jukka Lekkala   www.mit.tut.fi/MIT-4070   Yes  English 

    Prerequisites
    Code Course Credits M/R
    MIT-1016 MIT-1016 Measurement Technology 5 Recommendable
    MIT-4016 MIT-4016 Sensor Physics 7 Recommendable
    MIT-4036 MIT-4036 Microsensors 5 Recommendable

    Prequisite relations (Sign up to TUT Intranet required)

    Additional information about prerequisites
    Chemistry and biochemistry studies help understanding the biological part of biosensors.

    Remarks

  • Partial passing of course must be in connection with the same round of implementation.

  • The course is suitable for postgraduate studies.

    • Distance learning

  • ITC utilized during the course

    • - In information distribution via homepage, newsgroups or mailing lists, e.g. current issues, timetables
    - In compiling teaching material, particularly for online use or other electronic media
    - In compiling exercise, group or laboratory work
    - In distributing and/or returning exercise work, material etc

  • Estimate as a percentage of the implementation of the course

    • - Contact teaching: 70 %
    - Distance learning: 0 %
    - Proportion of a student's independent study: 30 %

    Scaling
    Methods of instructionHours
    Lectures 36
    Exercises 54

    Study materials Hours
    Lecture slides 17
    Biomolecular sensors 30

    Other scaledHours
    Exam/midterm exam 3
    Total sum 140

    Principles and starting points related to the instruction and learning of the course

  • Learning is based on lectures and exercises.

    • Course homepage

    Last modified 05.03.2007
    Modified byHeikki Jokinen