Course Catalog 2009-2010 International Basic Pori International Postgraduate Open University |Degrees|     |Study blocks|     |Courses|

Implementation 1

Lecture times and places:

Per 1 :
Monday 14 - 16, TB214
Friday 14 - 17, TC303
Tuesday 14 - 16, TC165

Description:

From this course the student will know how to do exact stochastic simulations, delayed stochastic simulations, and how to create models of delayed stochastic gene regulatory networks. Students will become familiar with detailed models and experimental results related to single gene expression and its underlying mechanisms. Also, the student will be introduced to basic concepts of cell type and cell differentiation and learn the latest modeling techniques in these topics.

Person responsible:

Andre Sanches Ribeiro

Assessment scale:

Numerical evaluation scale (1-5) will be used on the course

Methods of instruction:

Methods of instruction	Hours
Lectures	36.0
Excercises	36.0
Practical works	9.0

Other measurings
Sum of all	81.0

Contact teaching: 50 %
Distance learning: 0 %
Proportion of a student´s independent study: 50 %

Additional information of course implementation:

Content 1 week (2 lessons, 45 mins each + 90 min Exercises) SSA. Examples. 2 week (2 lessons, 45 mins each + 90 min Exercises): .Delayed SSA .Examples 3 week (2 lessons, 45 mins each + 90 min Exercises): .Single expression with the delayed SSA .Examples 4 week (2 lessons, 45 mins each + 90 min Exercises): .Ergodic sets, noisy attractors as cell types .Examples: the toggle switch. 5 week (2 lessons, 45 mins each + 90 min Exercises): .Stochastic models of cell differentiation. .Examples and applications: Self-repressed gene and the repressilator 6 week (2 lessons, 45 mins each + 90 min Exercises): .Examples and applications. The P53-Mdm2 feedback loop. A self-repressed gene that eliminates a toxin.