Course Catalog 2011-2012
International

Basic Pori International Postgraduate Open University

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Course Catalog 2011-2012

ASE-7816 Biosensors, 5 cr

Additional information

Suitable for postgraduate studies

Person responsible

Jukka Lekkala

Lessons

Study type P1 P2 P3 P4 Summer Implementations Lecture times and places
Lectures
Excercises
Laboratory work



 



 
 2 h/week
 1 h/week

+2 h/week
+2 h/week
 3 h/per



 
ASE-7816 2011-01 Thursday 8 - 10, SH108

Requirements

Passed exercises, laboratory work and examination.
Completion parts must belong to the same implementation

Learning outcomes

After having passed the study module the student will understand the physical operating principles of biosensors. He/she knows the basic terms and definitions. He/she understand the biology of the sensing elements and specific molecular recognition principles. The student is able to give examples of different biosensor structures and is able to understand and analyse measurement connections and amplifiers that have been used with them. The student can model and simulate the function of simple biosensors. He/she understands the limitations of the sensors. The student can list different biosensors and of their application areas.

Content

Content Core content Complementary knowledge Specialist knowledge
1. History of biosensor development, applications and requirements of biosensors.   Definition of concentrations, sampling principles    
2. Principles of molecular recognition, structure of enzyme and antibody, immunosensors, modeling of reactions, immobilization techniques.   Immune response, bacteria and viruses, self-assembled membranes   Molecular modeling, Langmuir-Blodgett -thin film technology  
3. Detection methods, electrodes, ISFET, optical sensors, Surface Plasmon Resonance (SPR) sensor, piezoelectric resonators and thermal sensors.   Principles of electrochemistry, operation principles of optical fibre sensors, modeling of SPR sensor.    
4. Miniaturization, biocompatibility, microanalyzers and BioMEMS structures.   Biomaterials, Micro ElectroMechanical systems (MEMS)   
5. Examples of commercial biosensors.      

Evaluation criteria for the course

The grade of the course is determined by examination. If the student knows the core material well, there is a possibility to pass the course with grade 3. The supplementing knowledge must be also known in order to reach a grade of 4 or 5. If in the core material there are minor shortcomings, the student will have an opportunity for the grade 1 or 2 depending on the amount of the shortcomings. Activity in exercises gives the opportunity for the additional points in the examination. If there are considerable shortcomings in the knowledge of the core material, the student will not pass the course.

Assessment scale:

Numerical evaluation scale (1-5) will be used on the course

Partial passing:

Completion parts must belong to the same implementation

Study material

Type Name Author ISBN URL Edition, availability, ... Examination material Language
Book   Biomolecular sensors   Gizeli and Lowe   0-7484-0791-X          English  
Book   Engineering Biosensors - Kinetics and Design Applications   Ajit Sadana   0-12-613763-3     Chapters 2 & 3      English  
Lecture slides   Biosensors   Jukka Lekkala            English  

Prerequisites

Course Mandatory/Advisable Description
MIT-4010 Sensor Physics Advisable    
MIT-4016 Sensor Physics Advisable    
MIT-4031 Microsensors Advisable    
MIT-4037 Microsensors Advisable    

Additional information about prerequisites
Chemistry and biochemistry studies help understanding the biological part of biosensors. The english courses are for international students.

Prerequisite relations (Requires logging in to POP)



Correspondence of content

Course Corresponds course  Description 
ASE-7816 Biosensors, 5 cr MIT-4076 Biosensors, 5 cr  
ASE-7816 Biosensors, 5 cr MIT-4070 Biosensors, 5 cr  

More precise information per implementation

Implementation Description Methods of instruction Implementation
ASE-7816 2011-01 Introduces basic principles and techniques used in biosensors. Gives information on applications.        

Last modified15.08.2012