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Course Catalog 2012-2013
BME-1906 Doctoral Seminar on BME, 5 cr
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Lessons
| Study type | P1 | P2 | P3 | P4 | Summer | Lecture times and places |
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Description:
State-of-the-art molecular approaches demonstrate the role of bioelectricity in the directionality and speed of cell migration, proliferation, apoptosis, differentiation, and orientation. New information indicates that electric fields play a role in initiating and coordinating complex regenerative responses in development and wound repair and that they may also have a part in cancer progression and metastasis. Book considers methods for detecting endogenous electric field gradients and studying applied electric fields in the lab. The book addresses bioelectricity’s roles in guiding cell behavior during morphogenesis and orchestrating higher order patterning. It also covers the response of stem cells to applied electric fields, which reveals bioelectricity as an exciting new player in tissue engineering and regenerative medicine. This book provides an in-depth exploration of how electric signals control corneal wound repair and skin re-epithelialization, angiogenesis, and inflammation. It also delves into the bioelectric responses of cells derived from the musculoskeletal system, bioelectrical guidance of neurons, and the beneficial application of voltage gradients to promote regeneration in the spinal cord. It concludes with a discussion of bioelectricity and cancer progression and the potential for novel cancer biomarkers, new methods for early detection, and bioelectricity-based therapies to target both the tumor and metastatic cancer cells. This multidisciplinary compilation will benefit biologists, biochemists, biomedical scientists, engineers, dermatologists, and clinicians, or anyone else interested in development, regeneration, cancer, and tissue engineering. It can also serve as an ideal textbook for students in biology, medicine, medical physiology, biophysics, and biomedical engineering.
Person responsible:
Jari Hyttinen
Assessment scale:
Evaluation scale passed/failed will be used on the course
Additional information of course implementation:
The exact implementation of the seminar is announced later. Seminar takes 2 periods. For more information about the times and topics of the seminar, contact the responsiple person of the implementation.