Learning to build protein models based on known structures of holologous proteins. The course aims at practical skills in the use of modelling software.
Contents
The emphasis is on hands-on experience in building homology-based models with the software package Insight II or Discovery Studio. Selecting template structures, preparing modelling alignments, and building, refining and evaluating models.
Teaching methods
Teaching method
Contact
Online
Lectures
4 h
0 h
Exercises
8 h
0 h
Independent work, approximately 140 h. Teachers will give students the exercises, and students will need to submit the molecular coordinates of the final models and a written report on each modelling process.