The course will impart advanced knowledge and understanding of the mechanisms and machinery of regulation of gene expression, emphasizing of eukaryotic genes, but also introducing material from studies of plant, fungal genes as well as of bacterial and viral gene expression.
Sisältö
Topics to be covered include the basal transcription machinery and regulation, chromatin and epigenetics, modification and procesing of RNAs, nucleocytoplasmic transport, translational machinery and regulation, RNA interference and RNA turnover, -omics and organellar gene expression. The course will be concept-based rather than methods-based, and it will link mechanistic knowledge to concepts from development, physiology and evolution.
Toteutustavat
Opetustapa
Paikalla
Verkossa
Luento-opetus
30 t
0 t
Students have to write six essees (about 1500 words) in the given topics in Finnish or English during the course.
Opetuskieli
englanti,
suomi
Finnish in the case all the students can speak Finnish.
Vaadittavat opintosuoritukset
Arviointi
ja arviointiperusteet
Numerolla 1-5.
Examination max. 30 points and essees max. 30 points, and to pass min. 30 points (1/5).
Suositellut suoritusajankohdat
4. vuoden kevät
Kirjallisuus/Oppimateriaali
Lewin's GENES X, Jocelyn E. Krebbs, Elliot S. Goldstein and Stephen T. Kilpatrick, 2011, Chapters 19-30