The course will familiarize students with gene regulatory elements as well as different analysis strategies and current software tools to identify most probable functional elements in DNA sequences.
Contents
Different levels of gene regulation; transcription factor binding sites and their matrix representation; regulatory modules; promoter databases; navigating in genome browsers and retrieving data from genome databases; various tools to analyze promoter sequences of coexpressed or related genes; comparative genomics approaches to identify conserved non-coding regions and conserved binding sites in orthologous genomic sequences.
Teaching methods
Teaching method
Contact
Online
Lectures
10 h
0 h
Lectures, independent Internet work and excercises.
Teaching language
English
Modes of study
Lectures (approx.10 h), independent Internet work and exercises, reporting in an on-line learning diary.
Evaluation
Pass/fail.
Recommended year of study
2. year autumn
2. year spring
Study materials
Course material on the internet, on-line manuals and articles as specified before and during the course.