Julkaisut
2017
Al-Samadi A, Awad S, Tuomainen K, Zhao Y, Salem A, Parikka M, Salo T.
Crosstalk between tongue carcinoma cells, extracellular vesicles, and immune cells in in vitro and in vivo models.
Oncotarget. 2017; 8:60123-60134.
Myllymäki H, Niskanen M, Oksanen KE, Sherwood E, Ahava M, Parikka M, Rämet M.
Identification of novel antigen candidates for a tuberculosis vaccine in the adult zebrafish (Danio rerio).
PLoS One. 2017 Jul 25;12(7):e0181942.
Bootorabi F, Manouchehri H, Changizi R, Barker H, Palazzo E, Saltari A, Parikka M, Pincelli C, Aspatwar A.
Zebrafish as a Model Organism for the Development of Drugs for Skin Cancer.
Int J Mol Sci. 2017 Jul 18;18(7).
Aspatwar A, Hammarén M, Koskinen S, Luukinen B, Barker H, Carta F, Supuran CT, Parikka M, Parkkila S.
β-CA-specific inhibitor dithiocarbamate Fc14-584B: a novel antimycobacterial agent with potential to treat drug-resistant tuberculosis.
J Enzyme Inhib Med Chem. 2017 Dec;32(1):832-840.
2016
Myllymäki H, Bäuerlein CA, Rämet M
The Zebrafish Breathes New Life into the Study of Tuberculosis.
Front Immunol ;2016. PMID: 27242801
Oksanen KE, Myllymäki H, Ahava MJ, Mäkinen L, Parikka M, Rämet M
DNA vaccination boosts Bacillus Calmette-Guérin protection against mycobacterial infection in zebrafish.
Dev Comp Immunol ;54(1)89-96, 2016. PMID: 26363085
2015
Aspatwar A, Tolvanen ME, Ojanen MJ, Barker HR, Saralahti AK, Bäuerlein CA, Ortutay C, Pan P, Kuuslahti M, Parikka M, Rämet M, Parkkila S
Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish
PLoS One. 2015 Jul 28;10(7):e0134263. doi: 10.1371/journal.pone.0134263. eCollection 2015
Saralahti A, Rämet M
Zebrafish and Streptococcal Infections
Scand J Immunol. 2015 Sep;82(3):174-83. doi: 10.1111/sji.12320
Myllymäki H, Niskanen M, Oksanen KE, Rämet M
Animal models in tuberculosis research – where is the beef?
Expert Opin Drug Discov. 2015;10(8):871-83. doi: 10.1517/17460441.2015.1049529. Epub 2015 Jun 13
Ojanen MJ, Turpeinen H, Cordova ZM, Hammarén MM, Harjula SK, Parikka M, Rämet M, Pesu M
The proprotein convertase subtilisin/kexin furinA regulates zebrafish host response against Mycobacterium marinum
Infect Immun. 2015 Apr;83(4):1431-42. doi: 10.1128/IAI.03135-14. Epub 2015 Jan 26
2014
Hammarén MM, Oksanen KE, Nisula HM, Luukinen BV, Pesu M, Rämet M, Parikka M
Adequate Th2-type response associates with restricted bacterial growth in latent mycobacterial infection of zebrafish
PLoS Pathog. 2014 Jun 26;10(6):e1004190. doi: 10.1371/journal.ppat.1004190. eCollection 2014 Jun
Saralahti A, Piippo H, Parikka M, Henriques-Normark B, Rämet M, Rounioja S
Adult zebrafish model for pneumococcal pathogenesis
Dev Comp Immunol. 2014, 42(2):345-53
2013
Oksanen KE, Halfpenny NJ, Sherwood E, Harjula SK, Hammarén MM, Ahava MJ, Pajula ET, Lahtinen MJ, Parikka M & Rämet M
An adult zebrafish model for preclinical tuberculosis vaccine development
Vaccine,31:5202-9
Taskinen B, Zmurko J, Ojanen M, Kukkurainen S, Parthiban M, Määttä JAE, Leppiniemi J, Jänis J, Parikka M, Turpeinen H, Rämet M, Pesu M, Johnson MS, Kulomaa MS, Airenne TT & Hytönen VP
Zebavidin – An avidin-like protein from zebrafish
PLoS ONE,8(10): e77207
Turpeinen H, Oksanen A, Kivinen V, Oksanen A, Kukkurainen S, Uusimäki A, Rämet M, Parikka M, Hytönen V, Nykter M & Pesu M
Proprotein Convertase Subtilisin/Kexin Type 7 (PCSK7) is essential for the zebrafish development and bioavailability of Transforming Growth Factor Beta 1a (TGFβ1a)
Journal of Biological Chemistry,288:36610-23
Aspatwar A, Tolvanen M, Jokitalo E, Parikka M, Ortutay C, Harjula SK, Rämet M, Vihinen M & Parkkila S
Altered cerebellum development and motor dysfunction in CARP VIII morphant zebrafish embryos
Hum Mol Genet. 2013 Feb 1;22(3):417-32
2012
Teittinen K, Parikka M, Latvala A, Junttila S, Laiho A, Korkeamäki H, Gröngroos T, Kurppa K, Turpeinen H, Pesu M, Gyenesei A, Rämet M & Lohi O
Knockdown of SAP30L disrupts early heart development and function in zebrafish
Journal of Cellular Biochemistry, 2012, 113:3843-3852
Lohi O, Parikka M & Rämet M
The zebrafish as a model for paediatric diseases
Acta Paediatrica. Epub Aug 24, 2012, doi: 10.1111/j.1651-2227.2012.02835.x
Parikka M, Vuoksio M, Harjula SK, Halfpenny N, Oksanen K, Lahtinen MJ, Pajula E, Iivanainen A, Pesu M & Rämet M
Mycobacterium marinum causes a latent infection that can be reactivated by gamma irradiation in adult zebrafish
PLoS Pathogens, 2012, 8:e1002944
Patterson H, Saralahti A, Parikka M, Dramsi S, Trieu-Cuot P, Poyart C, Rounioja S & Rämet M
Adult zebrafish model of bacterial meningitis in Streptococcus agalactiae infection
Developmental and Comparative Immunology, Epub Aug 4, 2012
Teittinen K, Grönroos T, Parikka M, Rämet M & Lohi O
The zebrafish as a tool in leukemia research
Leukemia Research, 2012, 36:1082-1088
Rounioja S, Saralahti A, Rantala L, Parikka M, Henriques-Normark B, Silvennoinen O, Rämet M
Defense of zebrafish embryos against Streptococcus pneumoniae infection is dependent on the phagocytic activity of leukocytes
Developmental and Comparative Immunology, 2012, 36(2):342-348
2011
Ulvila J, Vanha-aho LM, Kleino A, Vähä-Mäkilä M, Vuoksio M, Eskelinen S, Hultmark D, Kocks C, Hallman M, Parikka M & Rämet M
Cofilin regulator 14-3-3-zeta is an evolutionarily conserved protein required for phagocytosis and microbial resistance
Journal of Leukocyte Biology, 2011,89(5):649-659
2010
Hyvärinen J, Parikka M, Sormunen R, Rämet M, Tryggvason K, Kivirikko KI, Myllyharju J & Koivunen P
Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromized kidney function
Journal of Biological Chemistry, 2010, 285(53):42023-42032
Valanne S, Myllymäki H, Kallio J, Schmid M, Kleino A, Murumägi A, Airaksinen L, Kotipelto T, Kaustio M, Ulvila J, Esfahani S, Engström Y, Silvennoinen O, Hultmark D, Parikka M & Rämet M
Genome-wide RNAi in Drosophila cells identifies G protein-coupled receptor kinase 2 as an evolutionary conserved regulator of the NF-kB signaling
Journal of Immunology, 2010, 184:6188-6198
