Keijo Viiri

Latest publications

• Comparative proteomics analysis of the mouse mini-gut organoid: insights into markers of gluten challenge from celiac disease intestinal biopsies

  Moulder, R., Bhosale, S. D., Viiri, K. & Lahesmaa, R., 2024, In: Frontiers in Molecular Biosciences. 11, 15 p., 1446822.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Transcriptomic analysis of intestine following administration of a transglutaminase 2 inhibitor to prevent gluten-induced intestinal damage in celiac disease

  CEC-3 Investigators, Dotsenko, V., Tewes, B., Hils, M., Pasternack, R., Isola, J., Taavela, J., Popp, A., Sarin, J., Huhtala, H., Hiltunen, P., Zimmermann, T., Mohrbacher, R., Greinwald, R., Lundin, K. E. A., Schuppan, D., Mäki, M. & Viiri, K., 2024, In: Nature Immunology. 25, p. 1218–1230 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Human intestinal organoid models for celiac disease research

  Dotsenko, V., Sioofy-Khojine, A. B., Hyöty, H. & Viiri, K., 2023, Celiac Disease. Castellanos-Rubio, A. & Galluzzi, L. (eds.). Academic Press, p. 173-193 21 p. (Methods in Cell Biology; vol. 179).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific › peer-review

• The Oral Transglutaminase 2 Inhibitor ZED1227 Accumulates in the Villous Enterocytes in Celiac Disease Patients during Gluten Challenge and Drug Treatment

  Isola, J., Mäki, M., Hils, M., Pasternack, R., Viiri, K., Dotsenko, V., Montonen, T., Zimmermann, T., Mohrbacher, R., Greinwald, R. & Schuppan, D., Jun 2023, In: International Journal of Molecular Sciences. 24, 13, 10815.

  Research output: Contribution to journal › Article › Scientific › peer-review

• G2/M checkpoint regulation and apoptosis facilitate the nuclear egress of parvoviral capsids

  Mattola, S., Mäntylä, E., Aho, V., Salminen, S., Leclerc, S., Oittinen, M., Salokas, K., Järvensivu, J., Hakanen, S., Ihalainen, T. O., Viiri, K. & Vihinen-Ranta, M., 2022, In: Frontiers in cell and developmental biology. 10, December, 21 p., 1070599.

  Research output: Contribution to journal › Article › Scientific › peer-review

• JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation

  Tavares, M., Khandelwal, G., Muter, J., Viiri, K., Beltran, M., Brosens, J. & Jenner, R., 31 May 2022, In: Cell Reports. 39, 9, 21 p., 110889.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Apolipoprotein A4 defines the villus-crypt border in duodenal specimens for celiac disease morphometry

  Taavela, J., Viiri, K., Välimäki, A., Sarin, J., Salonoja, K., Mäki, M. & Isola, J., 29 Jul 2021, In: Frontiers in Immunology. 12, 10 p., 713854.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Genome-Wide Transcriptomic Analysis of Intestinal Mucosa in Celiac Disease Patients on a Gluten-Free Diet and Postgluten Challenge

  Dotsenko, V., Mäki, M., Viiri, K., Oittinen, M., Taavela, J., Popp, A., Peräaho, M., Staff, S., Sarin, J., Leon, F. & Isola, J., 2021, In: Cellular And Molecular Gastroenterology And Hepatology. 11, 1, p. 13-32 20 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Polycomb Repressive Complex 2 Regulates Genes Necessary for Intestinal Microfold Cell (M Cell) Development

  George, J. J., Oittinen, M., Martin-Diaz, L., Zapilko, V., Iqbal, S., Rintakangas, T., Arrojo Martins, F. T., Niskanen, H., Katajisto, P., Kaikkonen, M. U. & Viiri, K., 2021, In: Cellular And Molecular Gastroenterology And Hepatology. 12, 3, p. 873-889 17 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Prc2 regulated atoh8 is a regulator of intestinal microfold cell (M cell) differentiation

  George, J. J., Martin‐Diaz, L., Ojanen, M. J. T., Gasa, R., Pesu, M. & Viiri, K., 2021, In: International Journal of Molecular Sciences. 22, 17, 9355.

  Research output: Contribution to journal › Article › Scientific › peer-review