Nonappa Nonappa
About me
I am a passionate researcher, dedicated teacher, and inspiring mentor. I have a diverse background spanning multiple fields, including organic and supramolecular chemistry, nanoparticle self-assembly, cryogenic transmission electron microscopy, and extracellular matrix design for breast cancer tissue culture. I am leading a multidisciplinary team of researchers at the interface of materials science and biomedical sciences. We focus on efficiently controlling the structure and properties with the highest possible precision. We develop Lab-on-a-chip-based sustainable in vitro preclinical models for personalized and precision breast cancer disease and diagnostic platforms. We fabricate bio-based short-distance optical fibers and microlasers in the optics and photonics areas. Beyond material development, we are actively engaged in advanced electron microscopy imaging, including cryogenic transmission electron microscopy (Cryo-TEM), electron tomography, and in situ electron microscopy. For more information, see our Research Page and Publications.
Fields of expertise
- Bio-based materials for optics and photonics
- Breast cancer disease and diagnostic models
- Precision nanomaterials
- Advanced transmission electron microscopy
Research unit
Research career
Current position
- 03.08.2020-Present: Associate Professor (tenure track) in Nanochemistry, Faculty of Engineering and Natural Sciences, Tampere University, Tampere, Finland.
Academic degrees and titles
- 19.10.2018: Abilitazione Scientifica Nationale (ASN), CHIM/07-Fondamenti Chimici delle Tecnologie, MIUR, Italy.
- 26.05.2017: Title of Docent in Soft Matter Microscopy, School of Science, Department of Applied Physics, Aalto University, Finland
- 13.12.2008: Ph.D. in Organic Chemistry, Department of Organic Chemistry, Indian Institute of Science, Bangalore, India.
- 24.05.2003: Master of Science (M.Sc. in Chemistry), Department of Chemistry, Mangalore University, Karnataka, India.
- 19.06.2001: Bachelor of Science (B.Sc. in Chemistry, Botany, and Pharmacognosy as equal options), Shri Dharmasthala Manjunatheshwara College, Ujire, Karnataka, India.
- 10.11.2020: Executive Master of Business Administration, Quantic School of Business and Technology, Washington D.C., USA.
- 04.05.2019: Fundamentals of Business, Quantic School of Business and Technology, Washington D.C., USA
Previous research experience
- 26.05.2017-31.07.2020: Research Fellow and Docent, Department of Applied Physics, School of Science, Aalto University, Finland
- 01.08.2012-25.05.2017: Postdoctoral Researcher, Department of Applied Physics, School of Science, Aalto University, Finland.
- 15.02.2009-31.07.2012: Postdoctoral Researcher, Department of Chemistry, University of Jyväskylä, Finland.
- 15.08.2008-14.02.2009: Visiting Ph.D. student, SITRA fellowship, Department of Chemistry, University of Jyväskylä, Finland
- 23.09.2007-22.03.2008: Visiting Ph.D. student, CIMO fellowship, Department of Chemistry, University of Jyväskylä, Finland
Selected publications
Visit our research group page for more details: https://research.tuni.fi/png/
- Bioinspired Functionally Graded Composite Assembled Using Cellulose Nanocrystals and Genetically Engineered Proteins with Controlled Biomineralization. P.Mohammadi, J.-A. Gandier, Nonappa, W. Wagermaier, A. Miserez, M. Penttilä, Adv. Mater. 2021, 33, 2102658 [Link]
- Luminescent Gold Nanocluster‐Methylcellulose Composite Optical Fibers with Low Attenuation Coefficient and High Photostability. V. Hynninen, S. Chandra, S. Das, M. Amini, Y. Dai, S. Lepikko, P. Mohammadi, S. Hietala, R. H. A. Ras, Z. Sun, O. Ikkala, Nonappa, Small 2021, 17, 2005205 [Link]
- Nanocellulose: Recent fundamental advances and emerging biological and biomimicking applications. K. Heise, E. Kontturi, Y, Allahverdiyeva, T. Tammelin, M. B. Linder, Nonappa, O. Ikkala. Adv. Mater. 2021, 2004349 [Link].
- DNA Origami Templated Growth of Multilamellar Lipid Assemblies. S. Julin, Nonappa, B. Shen V. Linko M. A. Kostiainen, Angewandte. Chem. Intl. Ed. 2021. [Link]
- Luminescent gold nanoclusters for bioimaging applications. Nonappa, Beil. J. Nanotechnol. 2020, 11, 533–546 [Link].
- Atomically Precise Nanocluster Assemblies Encapsulating Plasmonic Gold Nanorods, A. Chakraborty, A. C. Fernandez, A. Som, B. Mondal, G. Natarajan, G. Paramasivam, T. Lahtinen, H. Häkkinen, Nonappa, T. Pradeep. Angew. Chem. Int. Ed. 2018, 57, 6522-6526 [Link].
- Polymer Nanowires with Highly Precise Internal Morphology and Topography, Théophile Pelras, Clare S Mahon, Nonappa, Olli Ikkala, André H Gröschel, Markus Müllner, J. Am. Chem. Soc. 2018, 140, 12736-12740 [Link]
- Hydrogen bonding directed colloidal self-assembly of nanoparticles into 2D crystals, capsids, and supracolloidal assemblies. Nonappa, O. Ikkala, Adv. Funct. Mater. 2018, 28, 1704328 [Link].
- Reversible supracolloidal self-assembly of cobalt nanoparticles to capsids and superstructures. Nonappa, J. S. Haataja, J. V. I Timonen, S. Malola, P. Engelhardt, N. Houbenov, M. Lahtinen, H. Häkkinen, O. Ikkala, Angew. Chem. Int. Ed. 2017, 56, 6473-6477 [Link].
- Template-free supracolloidal self-assembly of atomically precise gold nanoclusters: From 2D colloidal crystals to spherical capsids. Nonappa, T. Lahtinen, J. S. Haataja, T. –R. Tero, H. Häkkinen, O. Ikkala, Angew. Chem. Int. Ed. 2016, 55, 16035–16038 [Link].
Latest publications
Accelerated Engineering of ELP-Based Materials through Hybrid Biomimetic-De Novo Predictive Molecular Design
Laakko, T., Korkealaakso, A., Yildirir, B. F., Batys, P., Liljeström, V., Hokkanen, A., Nonappa, Penttilä, M., Laukkanen, A., Miserez, A., Södergård, C. & Mohammadi, P., 11 Jul 2024, In: Advanced Materials. 36, 28, 2312299.Research output: Contribution to journal › Article › Scientific › peer-review
Golden Plasmophores with Tunable Photoluminescence and Outstanding Thermal and Photothermal Stability
Gharib, M., Yates, A. J., Sanders, S., Gebauer, J., Graf, S., Ziefuß, A. R., Nonappa, Kassier, G., Rehbock, C., Barcikowski, S., Weller, H., Alabastri, A., Nordlander, P., Parak, W. J. & Chakraborty, I., May 2024, In: Advanced Optical Materials. 12, 14, 2302833.Research output: Contribution to journal › Article › Scientific › peer-review
In situ size dynamics and manipulation of nanoparticle interaction under electron beam irradiation
Zulfiqar, A., Honkanen, M., Vippola, M. & Nonappa, N., 17 Oct 2024, The 17th European Microscopy Congress (EMC 2024). Qvortrup, K. & Weede, K. (eds.). EDP Sciences, 3 p. 08012. (BIO Web of Conferences; vol. 129).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific
In Situ TEM Imaging Reveals the Dynamic Interplay Between Attraction, Repulsion and Sequential Attraction-Repulsion in Gold Nanoparticles
Zulfiqar, A., Honkanen, M., Nonappa & Vippola, M., 2024, (E-pub ahead of print) In: Small.Research output: Contribution to journal › Article › Scientific › peer-review
Interparticle Antigalvanic Reactions of Atomically Precise Silver Nanoclusters with Plasmonic Gold Nanoparticles: Interfacial Control of Atomic Exchange
Bose, P., Roy, J., Khokhar, V., Mondal, B., Natarajan, G., Manna, S., Yadav, V., Nyayban, A., Yamijala, S. S. R. K. C., Nonappa & Pradeep, T., 2024, In: Chemistry of Materials. 36, 15, p. 7581-7594Research output: Contribution to journal › Article › Scientific › peer-review
Invasion/chemotaxis- and extravasation-chip models for breast cancer bone metastasis
Firatligil-Yildirir, B., Bati-Ayaz, G., Nonappa, Pesen-Okvur, D. & Yalcin-Ozuysal, O., Oct 2024, In: PLoS ONE. 19, 10, e0309285.Research output: Contribution to journal › Article › Scientific › peer-review
Mechanically Robust Biopolymer Optical Fibers with Enhanced Performance in the Near-Infrared Region
Patrakka, J., Hynninen, V., Lahtinen, M., Hokkanen, A., Orelma, H., Sun, Z. & Nonappa, N., 14 Aug 2024, In: ACS Applied Materials and Interfaces. 16, 32, p. 42704-42716 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Nanocluster reaction-driven in situ transformation of colloidal nanoparticles to mesostructures
Bose, P., Srikrishnarka, P., Paatelainen, M., Nonappa, N., Kini, A. R., Som, A. & Pradeep, T., 2024, (E-pub ahead of print) In: Nanoscale.Research output: Contribution to journal › Article › Scientific › peer-review
Platinum-Grafted Twenty-Five Atom Gold Nanoclusters for Robust Hydrogen Evolution
Mymoona, P., Rival, J. V., Nonappa, Shibu, E. S. & Jeyabharathi, C., 2024, In: Small. 20, 23, 2308610.Research output: Contribution to journal › Article › Scientific › peer-review
Relationship between depth-wise refractive index and biomechanical properties of human articular cartilage
Khan, B., Nippolainen, E., Shahini, F., Nonappa, N., Popov, A., Töyräs, J. & Afara, I. O., 20 Sept 2024, In: Journal of Biomedical Optics. 29, 9, 12 p., 095003.Research output: Contribution to journal › Article › Scientific › peer-review