Pauli Losoi

I mostly teach thermal sciences, or thermodynamics, fluid mechanics, and heat transfer. I also give lectures on industrial-scale bioreactors and teach how chemical reaction engineering can be applied to energy carrier processes (biorefining, catalytic transformations). I study the modeling of CO2 capture and the modeling of large-scale bioreactors.

Modeling of CO2 capture, modeling of industrial-scale bioreactors

energy engineering, thermal sciences, bioengineering

• Modeling large-scale bioreactors with diffusion equations. Part I: Predicting axial dispersion coefficient and mixing times. Losoi P., Konttinen J., Santala V. (2024). Biotechnology and Bioengineering, 121, 1060–1075.. https://doi.org/10.1002/bit.28632 
• Modeling large-scale bioreactors with diffusion equations. Part II: Characterizing substrate, oxygen, temperature, carbon dioxide, and pH profiles. Losoi P., Konttinen J., Santala V. (2024). Biotechnology and Bioengineering, 121, 1102–1117. https://doi.org/10.1002/bit.28635 
• Substantial gradient mitigation in simulated large-scale bioreactors by optimally placed multiple feed points. Losoi P., Konttinen J., Santala V. (2022). Biotechnology and Bioengineering, 119, 3549-3566. https://doi.org/10.1002/bit.28232 
• Enhanced Population Control in a Synthetic Bacterial Consortium by Interconnected Carbon Cross-Feeding. Losoi P., Santala V., Santala S. (2019). ACS Synthetic Biology, 8(12), 2642-2650. https://doi.org/10.1021/acssynbio.9b00316