BMT-72106 Cellular Biophysics , 5 cr
Person responsible
Soile Nymark
Lessons
| Implementation | Period | Person responsible | Requirements |
| BMT-72106 2019-01 | 4 |
Julia Johansson Soile Nymark Aapo Tervonen |
Accepted assignments, excercises, and final exam. |
Learning Outcomes
Student can explain the principles of cellular electrophysiology and mechanobiology, and their measurement techniques. Student understands the fundamentals of biomechanics of the extracellular environment (extracellular matrix: its components), cellular mechanics (force generation and force sensing), electrophysiological properties of cells and tissues as well as the relevant cellular components (ion channels, transporters). Student can analyze, calculate and model mechanobiological and electrophysiological phenomena at the cellular level.
Content
| Content | Core content | Complementary knowledge | Specialist knowledge |
| 1. | Extracellular matrix components | Cell attachement to the extracellular matrix | Extracellular matrix biomechanics |
| 2. | Force generation in the cells | Cellular components that are involved in the process | How forces are transduced within the cells |
| 3. | Force sensing in the cells | Cellular components that are involved in the process | How forces are sensed in the multicellular level |
| 4. | Electrophysiological properties of cells and tissues | Cellular components involved in the electrophysiological phenomena | Electrophysiological measurement techniques |
| 5. | Electrical signaling in the cell and between the cells | Electrical signal propagation in tissues | Measurement of electrical cell-cell signaling |
Instructions for students on how to achieve the learning outcomes
The final grade of the course is determined based on the assessment of all parts of the course. The weighting factors are: exam 66%, project works 33%, exercises up to 3 bonus points. 1: The student understands the basics of mechanobiology and electrophysiology. 3: Student can explain the basic principles of cellular electrophysiology, mechanobiology, and their measurement techniques, and describe the relevant cellular components. Student can utilize this knowledge in calculations of biophysical phenomena. 5: In addition to grade 3 requirements, student is able to apply the new knowledge and solve problems in cellular biophysics.
Assessment scale:
Numerical evaluation scale (0-5)
Partial passing:
Study material
| Type | Name | Author | ISBN | URL | Additional information | Examination material |
| Lecture slides | Lecture slides | Yes |
Prerequisites
| Course | Mandatory/Advisable | Description |
| BMT-51016 Introduction to Cell and Molecular Biology | Mandatory |
Correspondence of content
| Course | Corresponds course | Description |
| BMT-72106 Cellular Biophysics , 5 cr | ELT-72106 Cellular Interactions, 5 cr |