Goal
GlassBoneS project aims to develop solution for maxillofacial bone augmentation procedures essential for dental implants when the patient does not have enough bone to attach the implantable screw, to which the dental prosthesis is attached. Utilizing multi-substituted hydroxyapatite powders, the GlassBoneS aims to create scaffolds through Ceramic Vat Polymerization. The challenge lies in achieving suitable mechanical properties with required high-temperature sintering, compromising bioactivity. GlassBoneS proposes solution by applying low-temperature sintering bioactive glass to coat hydroxyapatite particles. This approach preserves hydroxyapatite bioactivity but also enhances scaffold mechanical properties, while simultaneously addressing the threat of multi-drug resistant bacteria by incorporating trace elements into the bioactive glass.
Impact
According to the World Health Organization (WHO), less than half of the world's population is covered by essential healthcare services and progress is needed in developing affordable solutions. The GlassBoneS project aims continue to further develop materials obtained during AffordBoneS project (Horizon Europe Marie Skłodowska-Curie Actions) to provide personalized and affordable scaffolds for bone augmentation procedures to allow a larger population to have access to these treatments and improve their quality of the life. It is estimated that in Europe alone, 1.5 million augmentation procedures are required annually.
Funding source
Tampere University, Tampere Institute of Advanced Study